Cargando…

Hepatitis B Virus Middle Protein Enhances IL-6 Production via p38 MAPK/NF-κB Pathways in an ER Stress-Dependent Manner

During hepatitis B virus (HBV) infection, three viral envelope proteins of HBV are overexpressed in the endoplasmic reticulum (ER). The large S protein (LHBs) and truncated middle S protein (MHBs(t)) have been documented to play roles in regulating host gene expression and contribute to hepatic dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yang-Xia, Ren, Yan-Li, Fu, Hai-Jing, Zou, Ling, Yang, Ying, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951109/
https://www.ncbi.nlm.nih.gov/pubmed/27434097
http://dx.doi.org/10.1371/journal.pone.0159089