CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling

Benign prostate hyperplasia (BPH), an enlargement of the prostate common in aging in men, is associated with urinary voiding dysfunction manifest as Lower Urinary Tract Symptoms (LUTS). Although inflammation and abnormal smooth muscle contractions are known to play key roles in the development of LU...

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Detalles Bibliográficos
Autores principales: Rodríguez-Nieves, José A., Patalano, Susan C., Almanza, Diego, Gharaee-Kermani, Mehrnaz, Macoska, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951124/
https://www.ncbi.nlm.nih.gov/pubmed/27434301
http://dx.doi.org/10.1371/journal.pone.0159490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951124/
https://www.ncbi.nlm.nih.gov/pubmed/27434301
http://dx.doi.org/10.1371/journal.pone.0159490

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