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Direct mechanical stimulation of tip links in hair cells through DNA tethers

Mechanoelectrical transduction by hair cells commences with hair-bundle deflection, which is postulated to tense filamentous tip links connected to transduction channels. Because direct mechanical stimulation of tip links has not been experimentally possible, this hypothesis has not been tested. We...

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Detalles Bibliográficos
Autores principales: Basu, Aakash, Lagier, Samuel, Vologodskaia, Maria, Fabella, Brian A, Hudspeth, AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951189/
https://www.ncbi.nlm.nih.gov/pubmed/27331611
http://dx.doi.org/10.7554/eLife.16041

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