Cargando…
DYT1 dystonia increases risk taking in humans
It has been difficult to link synaptic modification to overt behavioral changes. Rodent models of DYT1 dystonia, a motor disorder caused by a single gene mutation, demonstrate increased long-term potentiation and decreased long-term depression in corticostriatal synapses. Computationally, such asymm...
Autores principales: | Arkadir, David, Radulescu, Angela, Raymond, Deborah, Lubarr, Naomi, Bressman, Susan B, Mazzoni, Pietro, Niv, Yael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951192/ https://www.ncbi.nlm.nih.gov/pubmed/27249418 http://dx.doi.org/10.7554/eLife.14155 |
Ejemplares similares
-
Opposing patterns of abnormal D1 and D2 receptor dependent cortico-striatal plasticity explain increased risk taking in patients with DYT1 dystonia
por: Gilbertson, Tom, et al.
Publicado: (2020) -
A role for cerebellum in the hereditary dystonia DYT1
por: Fremont, Rachel, et al.
Publicado: (2017) -
Spatial Discrimination Threshold Abnormalities are not Detected in a Pilot Study of DYT6 Dystonia Mutation Carriers
por: Deik, Andres F., et al.
Publicado: (2012) -
Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia
por: Zimmerman, Chelsea N., et al.
Publicado: (2017) -
DYT-TOR1A dystonia: an update on pathogenesis and treatment
por: Fan, Yuhang, et al.
Publicado: (2023)