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Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

Aldosterone (Aldo) is an independent risk factor for chronic kidney disease (CKD), and although Aldo directly induces renal tubular cell injury, the underlying mechanisms remain unclear. NLRP3 inflammasome and mitochondrial reactive oxygen species (ROS) have recently been implicated in various kinds...

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Detalles Bibliográficos
Autores principales:	Ding, Wei, Guo, Honglei, Xu, Chengyan, Wang, Bin, Zhang, Minmin, Ding, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951227/ https://www.ncbi.nlm.nih.gov/pubmed/27014913 http://dx.doi.org/10.18632/oncotarget.8243

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