Cargando…

Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR

Porcine circovirus type 2 (PCV2) infection caused PCV2-associated diseases (PCVAD) is one of the major emerging immunosuppression diseases in pig industry. In this study, we investigated how PCV2 inoculation increases interleukin (IL)-10 expression in porcine alveolar macrophages (PAMs). PCV2 inocul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Qian, Huang, Yong, Wang, Tongtong, Zhang, Xiujuan, Chen, Yu, Cui, Beibei, Li, Delong, Zhao, Xiaomin, Zhang, Wenlong, Chang, Lingling, Tong, Dewen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951228/ https://www.ncbi.nlm.nih.gov/pubmed/26883107 http://dx.doi.org/10.18632/oncotarget.7362

Ejemplares similares

Preclinical Detection of Porcine Circovirus Type 2 Infection Using an Ultrasensitive Nanoparticle DNA Probe-Based PCR Assay
por: Huang, Yong, et al.
Publicado: (2014)

Cap Is the Protease of the Porcine Circovirus 2
por: Yang, Xuechen, et al.
Publicado: (2022)

p53 signaling modulation of cell cycle arrest and viral replication in porcine circovirus type 2 infection cells
por: Xu, Dan, et al.
Publicado: (2016)

Porcine Circovirus Type 2 Rep Enhances IL-10 Production in Macrophages via Activation of p38-MAPK Pathway
por: Wu, Xingchen, et al.
Publicado: (2019)

Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway
por: Lu, Zheng, et al.
Publicado: (2018)

Interleukin-10 Promotes Porcine Circovirus Type 2 Persistent Infection in Mice and Aggravates the Tissue Lesions by Suppression of T Cell Infiltration
por: Du, Qian, et al.
Publicado: (2019)

The ultrasonically treated nanoliposomes containing PCV2 DNA vaccine expressing gC1qR binding site mutant Cap is efficient in mice
por: Du, Qian, et al.
Publicado: (2023)

Porcine Circovirus
por: Saikumar, G., et al.
Publicado: (2019)

gC1qR: A New Target for Cancer Immunotherapy
por: Lei, Yanna, et al.
Publicado: (2023)

Replication of porcine circoviruses
por: Faurez, Florence, et al.
Publicado: (2009)

Porcine Circoviruses and Xenotransplantation
por: Denner, Joachim, et al.
Publicado: (2017)

Porcine Circovirus Type 4 Strains Circulating in China Are Relatively Stable and Have Higher Homology with Mink Circovirus than Other Porcine Circovirus Types
por: Li, Xue, et al.
Publicado: (2022)

Recombinant Flagellin-Porcine Circovirus Type 2 Cap Fusion Protein Promotes Protective Immune Responses in Mice
por: Zhang, Chunyan, et al.
Publicado: (2015)

Serum investigation of antibodies against porcine circovirus 4 Rep and Cap protein in Jiangxi Province, China
por: Hu, Xifeng, et al.
Publicado: (2022)

Design and preliminary application of affinity peptide based on the structure of the porcine circovirus type II Capsid (PCV2 Cap)
por: Hao, Junfang, et al.
Publicado: (2019)

Revisiting Porcine Circovirus Disease Diagnostic Criteria in the Current Porcine Circovirus 2 Epidemiological Context
por: Segalés, Joaquim, et al.
Publicado: (2022)

Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein
por: Moorman, Jonathan P, et al.
Publicado: (2005)

First Molecular Detection and Genetic Analysis of a Novel Porcine Circovirus (Porcine Circovirus 4) in Dogs in the World
por: Zhang, Liu-Hui, et al.
Publicado: (2023)

Immunity Elicited by an Experimental Vaccine Based on Recombinant Flagellin-Porcine Circovirus Type 2 Cap Fusion Protein in Piglets
por: Zhu, Shanshan, et al.
Publicado: (2016)

Genetic Characterization of Porcine Circovirus Type 2 from Pigs with Porcine Circovirus Associated Diseases in Argentina
por: Pereda, Ariel, et al.
Publicado: (2011)

First report on identification and genomic analysis of a novel porcine circovirus (porcine circovirus 4) in cats
por: Xu, Tong, et al.
Publicado: (2023)

Nucleolar Phosphoprotein NPM1 Interacts With Porcine Circovirus Type 3 Cap Protein and Facilitates Viral Replication
por: Song, Jiangwei, et al.
Publicado: (2021)

Advances in Crosstalk between Porcine Circoviruses and Host
por: Niu, Guyu, et al.
Publicado: (2022)

GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells
por: Sünderhauf, Annika, et al.
Publicado: (2020)

Porcine Circovirus Type 3 Cap Inhibits Type I Interferon Induction Through Interaction With G3BP1
por: Zhang, Pengfei, et al.
Publicado: (2020)

Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage
por: Yang, Shunli, et al.
Publicado: (2019)

Mitochondrial Localization Signal of Porcine Circovirus Type 2 Capsid Protein Plays a Critical Role in Cap-Induced Apoptosis
por: Yu, Wanting, et al.
Publicado: (2021)

First detection and complete genome analysis of porcine circovirus‐like virus P1 and porcine circovirus‐2 in yak in China
por: Zhu, Jiaping, et al.
Publicado: (2022)

Prevalence of porcine circovirus-like agent P1 in Jiangsu, China
por: Wen, Libin, et al.
Publicado: (2011)

Test_QR
por: test, uni
Publicado: (2015)

Detection and molecular characterization of porcine circovirus type 2 from piglets with Porcine Circovirus Associated Diseases in Colombia
por: Rincón Monroy, Maria Antonia, et al.
Publicado: (2014)

An epidemiological investigation of porcine circovirus type 2 and porcine circovirus type 3 infections in Tianjin, North China
por: Wang, Shuai-Yong, et al.
Publicado: (2020)

Genomic Rearrangement and Recombination of Porcine Circovirus Type 2 and Porcine Circovirus-Like Virus P1 in China
por: Wen, Libin, et al.
Publicado: (2021)

Phylodynamic analysis of current Porcine circovirus 4 sequences: Does the porcine circoviruses evolutionary history repeat itself?
por: Faustini, Giulia, et al.
Publicado: (2022)

HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways
por: Song, Xiaotian, et al.
Publicado: (2016)

Recent Progress on Epidemiology and Pathobiology of Porcine Circovirus 3
por: Chen, Si, et al.
Publicado: (2021)

Emergence of porcine circovirus‐like viruses associated with porcine diarrheal disease in China
por: Liu, Xianhui, et al.
Publicado: (2021)

Mechanisms of circovirus immunosuppression and pathogenesis with a focus on porcine circovirus 2: a review
por: Fehér, Enikő, et al.
Publicado: (2023)

Surface Display of porcine circovirus type 2 antigen protein cap on the spores of bacillus subtilis 168: An effective mucosal vaccine candidate
por: Li, Weijie, et al.
Publicado: (2022)

Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88–NF-kappa B signaling pathway in porcine alveolar macrophages in vitro
por: Han, Junyuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0b814nq3p5ed1ko889rmbod10u