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Artificial antigen-presenting cells expressing AFP(158-166) peptide and interleukin-15 activate AFP-specific cytotoxic T lymphocytes

Professional antigen-presenting cells (APCs) are potent generators of tumor antigen-specific cytotoxic T lymphocytes (CTLs) for adoptive immunotherapy; however, generation of APCs is cumbersome, expensive, and subject to the tumor microenvironment. Artificial APCs (aAPCs) have been developed as a co...

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Detalles Bibliográficos
Autores principales: Sun, Longhao, Guo, Hao, Jiang, Ruoyu, Lu, Li, Liu, Tong, Zhang, Zhixiang, He, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951234/
https://www.ncbi.nlm.nih.gov/pubmed/27007051
http://dx.doi.org/10.18632/oncotarget.8198

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