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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells

T–lymphokine-activated killer cell–originated protein kinase (TOPK) and maternal embryonic leucine zipper kinase (MELK) have been reported to play critical roles in cancer cell proliferation and maintenance of stemness. In this study, we investigated possible roles of TOPK and MELK in kidney cancer...

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Detalles Bibliográficos
Autores principales: Kato, Taigo, Inoue, Hiroyuki, Imoto, Seiya, Tamada, Yoshinori, Miyamoto, Takashi, Matsuo, Yo, Nakamura, Yusuke, Park, Jae-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951240/
https://www.ncbi.nlm.nih.gov/pubmed/26933922
http://dx.doi.org/10.18632/oncotarget.7755

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