Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

Hypoxia-inducible factor-1α (HIF-1α) mediates the response to hypoxia or other stimuli, such as growth factors, including endothelin-1 (ET-1), to promote malignant progression in numerous tumors. The importance of cofactors that regulate HIF-1α signalling within tumor is not well understood. Here we...

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Detalles Bibliográficos
Autores principales: Cianfrocca, Roberta, Tocci, Piera, Rosanò, Laura, Caprara, Valentina, Sestito, Rosanna, Di Castro, Valeriana, Bagnato, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951250/
https://www.ncbi.nlm.nih.gov/pubmed/26909598
http://dx.doi.org/10.18632/oncotarget.7461

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