Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

Nonresolving inflammation in the intestine predisposes individuals to colitis-associated colorectal cancer (CAC), which leads to high morbidity and mortality. Here we show that genistein-27 (GEN-27), a derivative of genistein, inhibited proliferation of human colorectal cancer cells through inhibiti...

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Detalles Bibliográficos
Autores principales: Du, Qianming, Wang, Yajing, Liu, Chao, Wang, Hong, Fan, Huimin, Li, Yan, Wang, Jianing, Zhang, Xu, Lu, Jinrong, Ji, Hui, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951256/
https://www.ncbi.nlm.nih.gov/pubmed/26910375
http://dx.doi.org/10.18632/oncotarget.7554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951256/
https://www.ncbi.nlm.nih.gov/pubmed/26910375
http://dx.doi.org/10.18632/oncotarget.7554

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