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Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis
Nonresolving inflammation in the intestine predisposes individuals to colitis-associated colorectal cancer (CAC), which leads to high morbidity and mortality. Here we show that genistein-27 (GEN-27), a derivative of genistein, inhibited proliferation of human colorectal cancer cells through inhibiti...
Autores principales: | Du, Qianming, Wang, Yajing, Liu, Chao, Wang, Hong, Fan, Huimin, Li, Yan, Wang, Jianing, Zhang, Xu, Lu, Jinrong, Ji, Hui, Hu, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951256/ https://www.ncbi.nlm.nih.gov/pubmed/26910375 http://dx.doi.org/10.18632/oncotarget.7554 |
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