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PKCδ regulates integrin α(V)β(3) expression and transformed growth of K-ras dependent lung cancer cells
We have previously shown that Protein Kinase C delta (PKCδ) functions as a tumor promoter in non-small cell lung cancer (NSCLC), specifically in the context of K-ras addiction. Here we define a novel PKCδ -> integrin α(V)β(3)->Extracellular signal-Regulated Kinase (ERK) pathway that regulates...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951259/ https://www.ncbi.nlm.nih.gov/pubmed/26918447 http://dx.doi.org/10.18632/oncotarget.7560 |