Predicting hot spots in protein interfaces based on protrusion index, pseudo hydrophobicity and electron-ion interaction pseudopotential features

The identification of hot spots, a small subset of protein interfaces that accounts for the majority of binding free energy, is becoming more important for the research of drug design and cancer development. Based on our previous methods (APIS and KFC2), here we proposed a novel hot spot prediction...

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Detalles Bibliográficos
Autores principales: Xia, Junfeng, Yue, Zhenyu, Di, Yunqiang, Zhu, Xiaolei, Zheng, Chun-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951271/
https://www.ncbi.nlm.nih.gov/pubmed/26934646
http://dx.doi.org/10.18632/oncotarget.7695

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