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Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor

MELK is upregulated in various types of human cancer and is known to be associated with cancer progression, maintenance of stemness, and poor prognosis. OTS167, a MELK kinase inhibitor, shows potent growth-suppressive effect on human tumors in a xenograft model, but the detailed mode of action has n...

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Detalles Bibliográficos
Autores principales:	Chung, Suyoun, Kijima, Kyoko, Kudo, Aiko, Fujisawa, Yoshiko, Harada, Yosuke, Taira, Akiko, Takamatsu, Naofumi, Miyamoto, Takashi, Matsuo, Yo, Nakamura, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951280/ https://www.ncbi.nlm.nih.gov/pubmed/26918358 http://dx.doi.org/10.18632/oncotarget.7685

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