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eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells
Clusterin is a secretory heterodimeric glycoprotein and the overexpression of secretory clusterin (sCLU) promotes cancer cell proliferation and reduces chemosensitivity. Therefore, sCLU might be an effective target for anticancer therapy. In the current study, we identified eIF3f as a novel CLU-inte...
Autores principales: | Lee, Ji-Yeon, Kim, Hyun-Ji, Rho, Seung Bae, Lee, Seung-Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951308/ https://www.ncbi.nlm.nih.gov/pubmed/26988917 http://dx.doi.org/10.18632/oncotarget.8105 |
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