A pharmacokinetic and safety study of a fixed oral dose of enzastaurin HCl in native Chinese patients with refractory solid tumors and lymphoma

PURPOSE: This study was conducted to assess the pharmacokinetics and safety of enzastaurin in native Chinese patients with refractory solid tumors and lymphoma. METHODS: Eligible patients received 500 mg of enzastaurin orally once daily. The pharmacokinetics of enzastaurin and its metabolites were a...

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Detalles Bibliográficos
Autores principales: Li, Xueying, Fang, Xiaojie, Li, Su, Zhang, Weijing, Yang, Nong, Cui, Yimin, Huang, He, Cai, Ruiqing, Lin, Xiaoting, Fu, Xiaohong, Hong, Huangming, Lin, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951311/
https://www.ncbi.nlm.nih.gov/pubmed/26942463
http://dx.doi.org/10.18632/oncotarget.7875

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