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Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

Interstrand crosslinks (ICLs) are a highly toxic form of DNA damage. ICLs can interfere with vital biological processes requiring separation of the two DNA strands, such as replication and transcription. If ICLs are left unrepaired, it can lead to mutations, chromosome breakage and mitotic catastrop...

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Detalles Bibliográficos
Autores principales:	Lopez-Martinez, David, Liang, Chih-Chao, Cohn, Martin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951507/ https://www.ncbi.nlm.nih.gov/pubmed/27094386 http://dx.doi.org/10.1007/s00018-016-2218-x

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