Hypoxia-mediated impaired erythrocyte Lands’ Cycle is pathogenic for sickle cell disease

Although Lands’ cycle was discovered in 1958, its function and cellular regulation in membrane homeostasis under physiological and pathological conditions remain largely unknown. Nonbiased high throughput metabolomic profiling revealed that Lands’ cycle was impaired leading to significantly elevated...

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Detalles Bibliográficos
Autores principales: Wu, Hongyu, Bogdanov, Mikhail, Zhang, Yujin, Sun, Kaiqi, Zhao, Shushan, Song, Anren, Luo, Renna, Parchim, Nicholas F., Liu, Hong, Huang, Aji, Adebiyi, Morayo G., Jin, Jianping, Alexander, Danny C., Milburn, Michael V., Idowu, Modupe, Juneja, Harinder S., Kellems, Rodney E., Dowhan, William, Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951653/
https://www.ncbi.nlm.nih.gov/pubmed/27436223
http://dx.doi.org/10.1038/srep29637

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