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Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene

Calcium sulfate bone void fillers are increasingly being used for dead space management in infected arthroplasty revision surgery. The presence of these materials as loose beads close to the bearing surfaces of joint replacements gives the potential for them to enter the joint becoming trapped betwe...

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Autores principales: Cowie, Raelene M, Carbone, Silvia, Aiken, Sean, Cooper, John J, Jennings, Louise M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952026/
https://www.ncbi.nlm.nih.gov/pubmed/27312481
http://dx.doi.org/10.1177/0954411916651461
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author Cowie, Raelene M
Carbone, Silvia
Aiken, Sean
Cooper, John J
Jennings, Louise M
author_facet Cowie, Raelene M
Carbone, Silvia
Aiken, Sean
Cooper, John J
Jennings, Louise M
author_sort Cowie, Raelene M
collection PubMed
description Calcium sulfate bone void fillers are increasingly being used for dead space management in infected arthroplasty revision surgery. The presence of these materials as loose beads close to the bearing surfaces of joint replacements gives the potential for them to enter the joint becoming trapped between the articulating surfaces; the resulting damage to cobalt chrome counterfaces and the subsequent wear of ultra-high-molecular-weight polyethylene is unknown. In this study, third-body damage to cobalt chrome counterfaces was simulated using particles of the calcium sulfate bone void fillers Stimulan(®) (Biocomposites Ltd., Keele, UK) and Osteoset(®) (Wright Medical Technology, TN, USA) using a bespoke rig. Scratches on the cobalt chrome plates were quantified in terms of their density and mean lip height, and the damage caused by the bone void fillers was compared to that caused by particles of SmartSet GMV PMMA bone cement (DePuy Synthes, IN, USA). The surface damage from Stimulan(®) was below the resolution of the analysis technique used; SmartSet GMV caused 0.19 scratches/mm with a mean lip height of 0.03 µm; Osteoset(®) led to a significantly higher number (1.62 scratches/mm) of scratches with a higher mean lip height (0.04 µm). Wear tests of ultra-high-molecular-weight polyethylene were carried out in a six-station multi-axial pin on plate reciprocating rig against the damaged plates and compared to negative (highly polished) and positive control plates damaged with a diamond stylus (2 µm lip height). The wear of ultra-high-molecular-weight polyethylene was shown to be similar against the negative control plates and those damaged with third-body particles; there was a significantly higher (p < 0.001) rate of ultra-high-molecular-weight polyethylene wear against the positive control plates. This study showed that bone void fillers of similar composition can cause varying damage to cobalt chrome counterfaces. However, the lip heights of the scratches were not of sufficient magnitude to increase the wear of ultra-high-molecular-weight polyethylene above that of the negative controls.
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spelling pubmed-49520262016-07-28 Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene Cowie, Raelene M Carbone, Silvia Aiken, Sean Cooper, John J Jennings, Louise M Proc Inst Mech Eng H Original Articles Calcium sulfate bone void fillers are increasingly being used for dead space management in infected arthroplasty revision surgery. The presence of these materials as loose beads close to the bearing surfaces of joint replacements gives the potential for them to enter the joint becoming trapped between the articulating surfaces; the resulting damage to cobalt chrome counterfaces and the subsequent wear of ultra-high-molecular-weight polyethylene is unknown. In this study, third-body damage to cobalt chrome counterfaces was simulated using particles of the calcium sulfate bone void fillers Stimulan(®) (Biocomposites Ltd., Keele, UK) and Osteoset(®) (Wright Medical Technology, TN, USA) using a bespoke rig. Scratches on the cobalt chrome plates were quantified in terms of their density and mean lip height, and the damage caused by the bone void fillers was compared to that caused by particles of SmartSet GMV PMMA bone cement (DePuy Synthes, IN, USA). The surface damage from Stimulan(®) was below the resolution of the analysis technique used; SmartSet GMV caused 0.19 scratches/mm with a mean lip height of 0.03 µm; Osteoset(®) led to a significantly higher number (1.62 scratches/mm) of scratches with a higher mean lip height (0.04 µm). Wear tests of ultra-high-molecular-weight polyethylene were carried out in a six-station multi-axial pin on plate reciprocating rig against the damaged plates and compared to negative (highly polished) and positive control plates damaged with a diamond stylus (2 µm lip height). The wear of ultra-high-molecular-weight polyethylene was shown to be similar against the negative control plates and those damaged with third-body particles; there was a significantly higher (p < 0.001) rate of ultra-high-molecular-weight polyethylene wear against the positive control plates. This study showed that bone void fillers of similar composition can cause varying damage to cobalt chrome counterfaces. However, the lip heights of the scratches were not of sufficient magnitude to increase the wear of ultra-high-molecular-weight polyethylene above that of the negative controls. SAGE Publications 2016-06-16 2016-08 /pmc/articles/PMC4952026/ /pubmed/27312481 http://dx.doi.org/10.1177/0954411916651461 Text en © IMechE 2016 http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Cowie, Raelene M
Carbone, Silvia
Aiken, Sean
Cooper, John J
Jennings, Louise M
Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title_full Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title_fullStr Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title_full_unstemmed Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title_short Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
title_sort influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952026/
https://www.ncbi.nlm.nih.gov/pubmed/27312481
http://dx.doi.org/10.1177/0954411916651461
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