A short CD3/CD28 costimulation combined with IL-21 enhance the generation of human memory stem T cells for adoptive immunotherapy

BACKGROUND: Immunotherapy based on the adoptive transfer of gene modified T cells is an emerging approach for the induction of tumor-specific immune responses. Memory stem T cells, due to their enhanced antitumor and self-renewal capacity, have become potential candidate for adoptive T cell therapy...

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Detalles Bibliográficos
Autores principales: Alvarez-Fernández, C., Escribà-Garcia, L., Vidal, S., Sierra, J., Briones, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952071/
https://www.ncbi.nlm.nih.gov/pubmed/27435312
http://dx.doi.org/10.1186/s12967-016-0973-y

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