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The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target

BACKGROUND: The unfolded protein response (UPR) is activated following an endoplasmic reticulum (ER) stress. The aim of this study was to investigate the global expression of UPR genes in human OA chondrocytes in induced (I)-UPR conditions, and to explore the regulation and role of the UPR genes in...

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Detalles Bibliográficos
Autores principales:	Li, Ying-Hua, Tardif, Ginette, Hum, David, Kapoor, Mohit, Fahmi, Hassan, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952234/ https://www.ncbi.nlm.nih.gov/pubmed/27435272 http://dx.doi.org/10.1186/s13075-016-1070-6

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