Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network

BACKGROUND: Tumour necrosis factor (TNF) superfamily cytokines and their receptors regulate diverse immune system functions through a common set of signalling pathways. Genetic variants in and expression of individual TNF superfamily cytokines, receptors and signalling proteins have been associated...

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Detalles Bibliográficos
Autores principales: Richard, Arianne C., Peters, James E., Lee, James C., Vahedi, Golnaz, Schäffer, Alejandro A., Siegel, Richard M., Lyons, Paul A., Smith, Kenneth G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952362/
https://www.ncbi.nlm.nih.gov/pubmed/27435189
http://dx.doi.org/10.1186/s13073-016-0329-5

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