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Memantine augmentation in clozapine-refractory schizophrenia: a randomized, double-blind, placebo-controlled crossover study

BACKGROUND: Dysfunction of neuroplasticity due to N-methyl-d-aspartate (NMDA) receptor hypofunction may be a causal factor for memory and executive dysfunctioning in schizophrenia. Deregulation of NMDA transmission in the prefrontal cortex may also explain negative and positive symptoms. Clozapine a...

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Detalles Bibliográficos
Autores principales:	Veerman, S. R. T., Schulte, P. F. J., Smith, J. D., de Haan, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954262/ https://www.ncbi.nlm.nih.gov/pubmed/27048954 http://dx.doi.org/10.1017/S0033291716000398

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