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Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi

Recent estimates of the global burden of fungal disease suggest that that their incidence has been drastically underestimated and that mortality may rival that of malaria or tuberculosis. Azoles are the principal class of antifungal drug and the only available oral treatment for fungal disease. Rece...

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Detalles Bibliográficos
Autores principales: Bromley, Mike, Johns, Anna, Davies, Emma, Fraczek, Marcin, Mabey Gilsenan, Jane, Kurbatova, Natalya, Keays, Maria, Kapushesky, Misha, Gut, Marta, Gut, Ivo, Denning, David W., Bowyer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954691/
https://www.ncbi.nlm.nih.gov/pubmed/27438017
http://dx.doi.org/10.1371/journal.pone.0158724