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A genome-wide imaging-based screening to identify genes involved in synphilin-1 inclusion formation in Saccharomyces cerevisiae

Synphilin-1 is a major component of Parkinson’s disease (PD) inclusion bodies implicated in PD pathogenesis. However, the machinery controlling synphilin-1 inclusion formation remains unclear. Here, we investigated synphilin-1 inclusion formation using a systematic genome-wide, high-content imaging...

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Detalles Bibliográficos
Autores principales:	Zhao, Lei, Yang, Qian, Zheng, Ju, Zhu, Xuefeng, Hao, Xinxin, Song, Jia, Lebacq, Tom, Franssens, Vanessa, Winderickx, Joris, Nystrom, Thomas, Liu, Beidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954962/ https://www.ncbi.nlm.nih.gov/pubmed/27440388 http://dx.doi.org/10.1038/srep30134

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