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Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat
BACKGROUND: Olvanil (NE 19550) is a non-pungent synthetic analogue of capsaicin, the natural pungent ingredient of capsicum which activates the transient receptor potential vanilloid type-1 (TRPV1) channel and was developed as a potential analgesic compound. Olvanil has potent anti-hyperalgesic effe...
Autores principales: | Alsalem, Mohammad, Millns, Paul, Altarifi, Ahmad, El-Salem, Khalid, Chapman, Victoria, Kendall, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955132/ https://www.ncbi.nlm.nih.gov/pubmed/27439609 http://dx.doi.org/10.1186/s40360-016-0074-9 |
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