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Laboratory tests as short-term correlates of stroke
BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955202/ https://www.ncbi.nlm.nih.gov/pubmed/27439507 http://dx.doi.org/10.1186/s12883-016-0619-y |
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author | Sughrue, Trevor Swiernik, Michael A. Huang, Yang Brody, James P. |
author_facet | Sughrue, Trevor Swiernik, Michael A. Huang, Yang Brody, James P. |
author_sort | Sughrue, Trevor |
collection | PubMed |
description | BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke. RESULTS: We identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers. CONCLUSION: Several dozen laboratory tests are effective short-term correlates of stroke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12883-016-0619-y) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4955202 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49552022016-07-22 Laboratory tests as short-term correlates of stroke Sughrue, Trevor Swiernik, Michael A. Huang, Yang Brody, James P. BMC Neurol Research Article BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke. RESULTS: We identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers. CONCLUSION: Several dozen laboratory tests are effective short-term correlates of stroke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12883-016-0619-y) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-21 /pmc/articles/PMC4955202/ /pubmed/27439507 http://dx.doi.org/10.1186/s12883-016-0619-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sughrue, Trevor Swiernik, Michael A. Huang, Yang Brody, James P. Laboratory tests as short-term correlates of stroke |
title | Laboratory tests as short-term correlates of stroke |
title_full | Laboratory tests as short-term correlates of stroke |
title_fullStr | Laboratory tests as short-term correlates of stroke |
title_full_unstemmed | Laboratory tests as short-term correlates of stroke |
title_short | Laboratory tests as short-term correlates of stroke |
title_sort | laboratory tests as short-term correlates of stroke |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955202/ https://www.ncbi.nlm.nih.gov/pubmed/27439507 http://dx.doi.org/10.1186/s12883-016-0619-y |
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