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Laboratory tests as short-term correlates of stroke

BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examin...

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Autores principales: Sughrue, Trevor, Swiernik, Michael A., Huang, Yang, Brody, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955202/
https://www.ncbi.nlm.nih.gov/pubmed/27439507
http://dx.doi.org/10.1186/s12883-016-0619-y
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author Sughrue, Trevor
Swiernik, Michael A.
Huang, Yang
Brody, James P.
author_facet Sughrue, Trevor
Swiernik, Michael A.
Huang, Yang
Brody, James P.
author_sort Sughrue, Trevor
collection PubMed
description BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke. RESULTS: We identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers. CONCLUSION: Several dozen laboratory tests are effective short-term correlates of stroke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12883-016-0619-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-49552022016-07-22 Laboratory tests as short-term correlates of stroke Sughrue, Trevor Swiernik, Michael A. Huang, Yang Brody, James P. BMC Neurol Research Article BACKGROUND: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke. METHODS: We examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke. RESULTS: We identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers. CONCLUSION: Several dozen laboratory tests are effective short-term correlates of stroke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12883-016-0619-y) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-21 /pmc/articles/PMC4955202/ /pubmed/27439507 http://dx.doi.org/10.1186/s12883-016-0619-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sughrue, Trevor
Swiernik, Michael A.
Huang, Yang
Brody, James P.
Laboratory tests as short-term correlates of stroke
title Laboratory tests as short-term correlates of stroke
title_full Laboratory tests as short-term correlates of stroke
title_fullStr Laboratory tests as short-term correlates of stroke
title_full_unstemmed Laboratory tests as short-term correlates of stroke
title_short Laboratory tests as short-term correlates of stroke
title_sort laboratory tests as short-term correlates of stroke
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955202/
https://www.ncbi.nlm.nih.gov/pubmed/27439507
http://dx.doi.org/10.1186/s12883-016-0619-y
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