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Dealing with prognostic signature instability: a strategy illustrated for cardiovascular events in patients with end-stage renal disease

BACKGROUND: Identification of prognostic gene expression markers from clinical cohorts might help to better understand disease etiology. A set of potentially important markers can be automatically selected when linking gene expression covariates to a clinical endpoint by multivariable regression mod...

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Detalles Bibliográficos
Autores principales: Binder, Harald, Kurz, Thorsten, Teschner, Sven, Kreutz, Clemens, Geyer, Marcel, Donauer, Johannes, Kraemer-Guth, Annette, Timmer, Jens, Schumacher, Martin, Walz, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955222/
https://www.ncbi.nlm.nih.gov/pubmed/27439789
http://dx.doi.org/10.1186/s12920-016-0210-9