Synthesis of d‐ and l‐Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process

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The synthesis of substituted d‐phenylalanines in high yield and excellent optical purity, starting from inexpensive cinnamic acids, has been achieved with a novel one‐pot approach by coupling phenylalanine ammonia lyase (PAL) amination with a chemoenzymatic deracemization (based on stereoselective o...

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Detalles Bibliográficos
Autores principales: Parmeggiani, Fabio, Lovelock, Sarah L., Weise, Nicholas J., Ahmed, Syed T., Turner, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Zuschriften
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955227/
https://www.ncbi.nlm.nih.gov/pubmed/27478261
http://dx.doi.org/10.1002/ange.201410670
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