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In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy

BACKGROUND: Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) Class I molecules bind to peptide fragments of proteins degraded inside the cell and display them on the cell surface. We are interested in peptide-HLA complexes involving peptides that are derived from proteins spec...

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Detalles Bibliográficos
Autores principales:	Dhanik, Ankur, R. Kirshner, Jessica, MacDonald, Douglas, Thurston, Gavin, C. Lin, Hsin, J. Murphy, Andrew, Zhang, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955262/ https://www.ncbi.nlm.nih.gov/pubmed/27439771 http://dx.doi.org/10.1186/s12859-016-1150-2

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