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Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire

BACKGROUND: Congenital abnormalities constitute one of the major causes of infant mortality, particularly in developing countries. The aim of this study was to describe the epidemiology of congenital anomalies in Cote d’Ivoire. MATERIALS AND METHODS: It was a multicentric study of three academic hos...

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Autores principales: Kouame, Bertin Dibi, N’guetta-Brou, Isabelle Ama, Kouame, Guy Serge Yapo, Sounkere, Moufidath, Koffi, Maxime, Yaokreh, Jean Baptiste, Odehouri-Koudou, Thierry, Tembely, Samba, Dieth, Gaudens Atafi, Ouattara, Ossenou, Dick, Ruffin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955485/
https://www.ncbi.nlm.nih.gov/pubmed/25659551
http://dx.doi.org/10.4103/0189-6725.150983
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author Kouame, Bertin Dibi
N’guetta-Brou, Isabelle Ama
Kouame, Guy Serge Yapo
Sounkere, Moufidath
Koffi, Maxime
Yaokreh, Jean Baptiste
Odehouri-Koudou, Thierry
Tembely, Samba
Dieth, Gaudens Atafi
Ouattara, Ossenou
Dick, Ruffin
author_facet Kouame, Bertin Dibi
N’guetta-Brou, Isabelle Ama
Kouame, Guy Serge Yapo
Sounkere, Moufidath
Koffi, Maxime
Yaokreh, Jean Baptiste
Odehouri-Koudou, Thierry
Tembely, Samba
Dieth, Gaudens Atafi
Ouattara, Ossenou
Dick, Ruffin
author_sort Kouame, Bertin Dibi
collection PubMed
description BACKGROUND: Congenital abnormalities constitute one of the major causes of infant mortality, particularly in developing countries. The aim of this study was to describe the epidemiology of congenital anomalies in Cote d’Ivoire. MATERIALS AND METHODS: It was a multicentric study of three academic hospitals and the Heart Institute of Abidjan over 10 years. The epidemiologic Data concerned the Parturients, the annual frequency of congenital abnormalities. Distribution of the congenital abnormalities according to the organs, overall mortality and lethality of congenital abnormalities were evaluated. RESULTS: Over 10 years, 1.632 newborns with 1.725 congenital anomalies were recorded. Frequency was 172.5 congenital anomalies per annum. Parturients were less than 35 years in 33% of cases, multigravida in 20%, multiparous in 18% and had a low socio economic status in 96% of cases. Prenatal diagnosis of congenital anomalies was performed in 1.5%. Congenital anomalies were orthopedic in 34%, neurological in 17%, gastrointestinal in 15%, facial in 11.5%, parietal in 13%, urogenital in 9% and cardiac in 0.5% of cases. The overall mortality rate of congenital anomalies was 52% and gastroschisis was the most lethal disease with 100% mortality. CONCLUSION: This descriptive study reveals the low socio economic status of Parturients with congenital anomalies and their poor prenatal diagnosis. These factors explain the very high mortality of congenital anomalies due to a delay management in our country in which medical expenses were borne by parents and where technical platforms remain obsoletes for good resuscitation and neonatal surgery.
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spelling pubmed-49554852016-09-01 Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire Kouame, Bertin Dibi N’guetta-Brou, Isabelle Ama Kouame, Guy Serge Yapo Sounkere, Moufidath Koffi, Maxime Yaokreh, Jean Baptiste Odehouri-Koudou, Thierry Tembely, Samba Dieth, Gaudens Atafi Ouattara, Ossenou Dick, Ruffin Afr J Paediatr Surg Original Article BACKGROUND: Congenital abnormalities constitute one of the major causes of infant mortality, particularly in developing countries. The aim of this study was to describe the epidemiology of congenital anomalies in Cote d’Ivoire. MATERIALS AND METHODS: It was a multicentric study of three academic hospitals and the Heart Institute of Abidjan over 10 years. The epidemiologic Data concerned the Parturients, the annual frequency of congenital abnormalities. Distribution of the congenital abnormalities according to the organs, overall mortality and lethality of congenital abnormalities were evaluated. RESULTS: Over 10 years, 1.632 newborns with 1.725 congenital anomalies were recorded. Frequency was 172.5 congenital anomalies per annum. Parturients were less than 35 years in 33% of cases, multigravida in 20%, multiparous in 18% and had a low socio economic status in 96% of cases. Prenatal diagnosis of congenital anomalies was performed in 1.5%. Congenital anomalies were orthopedic in 34%, neurological in 17%, gastrointestinal in 15%, facial in 11.5%, parietal in 13%, urogenital in 9% and cardiac in 0.5% of cases. The overall mortality rate of congenital anomalies was 52% and gastroschisis was the most lethal disease with 100% mortality. CONCLUSION: This descriptive study reveals the low socio economic status of Parturients with congenital anomalies and their poor prenatal diagnosis. These factors explain the very high mortality of congenital anomalies due to a delay management in our country in which medical expenses were borne by parents and where technical platforms remain obsoletes for good resuscitation and neonatal surgery. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4955485/ /pubmed/25659551 http://dx.doi.org/10.4103/0189-6725.150983 Text en Copyright: © African Journal of Paediatric Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kouame, Bertin Dibi
N’guetta-Brou, Isabelle Ama
Kouame, Guy Serge Yapo
Sounkere, Moufidath
Koffi, Maxime
Yaokreh, Jean Baptiste
Odehouri-Koudou, Thierry
Tembely, Samba
Dieth, Gaudens Atafi
Ouattara, Ossenou
Dick, Ruffin
Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title_full Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title_fullStr Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title_full_unstemmed Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title_short Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote d’Ivoire
title_sort epidemiology of congenital abnormalities in west africa: results of a descriptive study in teaching hospitals in abidjan: cote d’ivoire
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955485/
https://www.ncbi.nlm.nih.gov/pubmed/25659551
http://dx.doi.org/10.4103/0189-6725.150983
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