Hydrophobic CDR3 residues promote the development of self-reactive T cells

Studies of individual T cells receptors (TCRs) have shed some light on structural features that underlie self-reactivity. However, general rules that predict whether TCRs are self-reactive have not been fully elucidated. Analyses of thymocytes expressing all V(β) family members show that the interfa...

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Detalles Bibliográficos
Autores principales: Stadinski, Brian D., Shekhar, Karthik, Gómez-Touriño, Iria, Jung, Jonathan, Sasaki, Katsuhiro, Sewell, Andrew K., Peakman, Mark, Chakraborty, Arup K., Huseby, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955740/
https://www.ncbi.nlm.nih.gov/pubmed/27348411
http://dx.doi.org/10.1038/ni.3491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955740/
https://www.ncbi.nlm.nih.gov/pubmed/27348411
http://dx.doi.org/10.1038/ni.3491

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