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Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical and thermal allodynia after burn injury
The primary complaint of burn victims is an intense, often devastating spontaneous pain, with persistence of mechanical and thermal allodynia. The transient receptor potential channels, TRPV1 and TRPA1, are expressed by a subset of nociceptive sensory neurons and contribute to inflammatory hypersens...
Autores principales: | Green, Dustin P, Ruparel, Shivani, Gao, Xiaoli, Ruparel, Nikita, Patil, Mayur, Akopian, Armen, Hargreaves, Kenneth M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955965/ https://www.ncbi.nlm.nih.gov/pubmed/27411353 http://dx.doi.org/10.1177/1744806916661725 |
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