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Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical and thermal allodynia after burn injury

The primary complaint of burn victims is an intense, often devastating spontaneous pain, with persistence of mechanical and thermal allodynia. The transient receptor potential channels, TRPV1 and TRPA1, are expressed by a subset of nociceptive sensory neurons and contribute to inflammatory hypersens...

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Detalles Bibliográficos
Autores principales: Green, Dustin P, Ruparel, Shivani, Gao, Xiaoli, Ruparel, Nikita, Patil, Mayur, Akopian, Armen, Hargreaves, Kenneth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955965/
https://www.ncbi.nlm.nih.gov/pubmed/27411353
http://dx.doi.org/10.1177/1744806916661725

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