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Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor-regulated calcitonin gene-related peptide expression in colitis-induced visceral pain
BACKGROUND: Visceral hypersensitivity is a complex pathophysiological paradigm with unclear mechanisms. Primary afferent neuronal plasticity marked by alterations in neuroactive compounds such as calcitonin gene-related peptide is suggested to underlie the heightened sensory responses. Signal transd...
Autores principales: | Hashmi, Fiza, Liu, Miao, Shen, Shanwei, Qiao, Li-Ya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955977/ https://www.ncbi.nlm.nih.gov/pubmed/27306412 http://dx.doi.org/10.1177/1744806916657088 |
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