Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD

Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...

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Detalles Bibliográficos
Autores principales: Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://www.ncbi.nlm.nih.gov/pubmed/27207510
http://dx.doi.org/10.2337/db16-0213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955986/
https://www.ncbi.nlm.nih.gov/pubmed/27207510
http://dx.doi.org/10.2337/db16-0213

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