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Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD
Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty liver disease using a mouse model of lipodystrophy...
Autores principales: | Softic, Samir, Boucher, Jeremie, Solheim, Marie H., Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P., Winnay, Jonathon, Perez-Atayde, Antonio R., Kahn, C. Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955986/ https://www.ncbi.nlm.nih.gov/pubmed/27207510 http://dx.doi.org/10.2337/db16-0213 |
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