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The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

INTRODUCTION: Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val(66)met genotype, gene expression, and serum levels), (b) early and recent life stre...

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Detalles Bibliográficos
Autores principales: Generaal, Ellen, Milaneschi, Yuri, Jansen, Rick, Elzinga, Bernet M, Dekker, Joost, Penninx, Brenda WJH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955993/
https://www.ncbi.nlm.nih.gov/pubmed/27145806
http://dx.doi.org/10.1177/1744806916646783