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Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine

BACKGROUND: On trigeminal ganglion neurons, pain-sensing P2X3 receptors are constitutively inhibited by brain natriuretic peptide via its natriuretic peptide receptor-A. This inhibition is associated with increased P2X3 serine phosphorylation and receptor redistribution to non-lipid raft membrane co...

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Detalles Bibliográficos
Autores principales:	Marchenkova, Anna, Vilotti, Sandra, Ntamati, Niels, van den Maagdenberg, Arn MJM, Nistri, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955999/ https://www.ncbi.nlm.nih.gov/pubmed/27175010 http://dx.doi.org/10.1177/1744806916646110

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