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Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting

Contribution of salt wasting and volume depletion to the pathogenesis of hypercalciuria and hyperphosphaturia is poorly understood. Pendrin/NCC double KO (pendrin/NCC-dKO) mice display severe salt wasting under basal conditions and develop profound volume depletion, prerenal renal failure, and metab...

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Detalles Bibliográficos
Autores principales: Soleimani, Manoocher, Barone, Sharon, Xu, Jie, Alshahrani, Saeed, Brooks, Marybeth, McCormack, Francis X., Smith, Roger D., Zahedi, Kamyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956050/
https://www.ncbi.nlm.nih.gov/pubmed/27442254
http://dx.doi.org/10.1371/journal.pone.0159804