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Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility
Membrane cholesterol levels play an important factor in regulating cell function. Sarcolemmal cholesterol is concentrated in lipid rafts and caveolae, which are flask-shaped invaginations of the plasma membrane. The scaffolding protein caveolin permits the enrichment of cholesterol in caveolae, and...
Autores principales: | Haque, Mohammed Z., McIntosh, Victoria J., Abou Samra, Abdul B., Mohammad, Ramzi M., Lasley, Robert D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956108/ https://www.ncbi.nlm.nih.gov/pubmed/27441649 http://dx.doi.org/10.1371/journal.pone.0154151 |
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