Regulation of Thrombin-Induced Lung Endothelial Cell Barrier Disruption by Protein Kinase C Delta

Protein Kinase C (PKC) plays a significant role in thrombin-induced loss of endothelial cell (EC) barrier integrity; however, the existence of more than 10 isozymes of PKC and tissue–specific isoform expression has limited our understanding of this important second messenger in vascular homeostasis....

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Detalles Bibliográficos
Autores principales: Xie, Lishi, Chiang, Eddie T., Wu, Xiaomin, Kelly, Gabriel T., Kanteti, Prasad, Singleton, Patrick A., Camp, Sara M., Zhou, Tingting, Dudek, Steven M., Natarajan, Viswanathan, Wang, Ting, Black, Steven M., Garcia, Joe G. N., Jacobson, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956111/
https://www.ncbi.nlm.nih.gov/pubmed/27442243
http://dx.doi.org/10.1371/journal.pone.0158865

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