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Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis

Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR1 gene with reduction of newborn kidney size and function in heterozygotes and neonatal lethality with kidney defects in homozygotes. How OSR1 regulates...

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Detalles Bibliográficos
Autores principales: Xu, Jingyue, Liu, Han, Chai, Ok Hee, Lan, Yu, Jiang, Rulang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956120/
https://www.ncbi.nlm.nih.gov/pubmed/27442016
http://dx.doi.org/10.1371/journal.pone.0159597

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