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Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis
Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR1 gene with reduction of newborn kidney size and function in heterozygotes and neonatal lethality with kidney defects in homozygotes. How OSR1 regulates...
Autores principales: | Xu, Jingyue, Liu, Han, Chai, Ok Hee, Lan, Yu, Jiang, Rulang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956120/ https://www.ncbi.nlm.nih.gov/pubmed/27442016 http://dx.doi.org/10.1371/journal.pone.0159597 |
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