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Peripheral nerve injury induces loss of nociceptive neuron-specific Gαi-interacting protein in neuropathic pain rat

BACKGROUND: Gαi-interacting protein (GINIP) is expressed specifically in dorsal root ganglion (DRG) neurons and functions in modulation of peripheral gamma-aminobutyric acid B receptor (GBR). Genetic deletion of GINIP leads to impaired responsiveness to GBR agonist-mediated analgesia in rodent. It i...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Wang, Fei, Fischer, Gregory, Hogan, Quinn H., Yu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956147/
https://www.ncbi.nlm.nih.gov/pubmed/27145804
http://dx.doi.org/10.1177/1744806916646380