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Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice

ENU mutagenesis is a powerful method for generating novel lines of mice that are informative with respect to both fundamental biological processes and human disease. Rapid developments in genomic technology have made the task of identifying causal mutations by positional cloning remarkably efficient...

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Detalles Bibliográficos
Autores principales:	Gallego-Llamas, Jabier, Timms, Andrew E., Pitstick, Rose, Peters, Janet, Carlson, George A., Beier, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956170/ https://www.ncbi.nlm.nih.gov/pubmed/27441645 http://dx.doi.org/10.1371/journal.pone.0159377

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