Cargando…
Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants w...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956208/ https://www.ncbi.nlm.nih.gov/pubmed/27441722 http://dx.doi.org/10.1371/journal.pone.0158489 |
_version_ | 1782443999192154112 |
---|---|
author | Salinero-Fort, M. A. Burgos-Lunar, C. Lahoz, C. Mostaza, J. M. Abánades-Herranz, J. C. Laguna-Cuesta, F. Estirado-de Cabo, E. García-Iglesias, F. González-Alegre, T. Fernández-Puntero, B. Montesano-Sánchez, L. Vicent-López, D. Cornejo-del Río, V. Fernández-García, P. J. Sánchez-Arroyo, V. Sabín-Rodríguez, C. López-López, S. Patrón-Barandio, P. Gómez-Campelo, P. |
author_facet | Salinero-Fort, M. A. Burgos-Lunar, C. Lahoz, C. Mostaza, J. M. Abánades-Herranz, J. C. Laguna-Cuesta, F. Estirado-de Cabo, E. García-Iglesias, F. González-Alegre, T. Fernández-Puntero, B. Montesano-Sánchez, L. Vicent-López, D. Cornejo-del Río, V. Fernández-García, P. J. Sánchez-Arroyo, V. Sabín-Rodríguez, C. López-López, S. Patrón-Barandio, P. Gómez-Campelo, P. |
author_sort | Salinero-Fort, M. A. |
collection | PubMed |
description | AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants with UT2DM, ranged between 45–74 years and lived in two districts in the north of metropolitan Madrid (Spain). The FINDRISC and MADRISC scores were evaluated using the area under the receiver operating characteristic curve method (ROC-AUC). Four different gold standards were used for UT2DM and any dysglycaemia, as follows: fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), HbA1c, and OGTT or HbA1c. Dysglycaemia and UT2DM were defined according to American Diabetes Association criteria. RESULTS: The study population comprised 1,426 participants (832 females and 594 males) with a mean age of 62 years (SD = 6.1). When HbA1c or OGTT criteria were used, the prevalence of UT2DM was 7.4% (10.4% in men and 5.2% in women; p<0.01) and the FINDRISC ROC-AUC for UT2DM was 0.72 (95% CI, 0.69–0.74). The optimal cut-off point was ≥13 (sensitivity = 63.8%, specificity = 65.1%). The ROC-AUC of MADRISC was 0.76 (95% CI, 0.72–0.81) with ≥13 as the optimal cut-off point (sensitivity = 84.8%, specificity = 54.6%). FINDRISC score ≥12 for detecting any dysglycaemia offered the best cut-off point when HbA1c alone or OGTT and HbA1c were the criteria used. CONCLUSIONS: FINDRISC proved to be a useful instrument in screening for dysglycaemia and UT2DM. In the screening of UT2DM, the simplified MADRISC performed as well as FINDRISC. |
format | Online Article Text |
id | pubmed-4956208 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-49562082016-08-08 Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study Salinero-Fort, M. A. Burgos-Lunar, C. Lahoz, C. Mostaza, J. M. Abánades-Herranz, J. C. Laguna-Cuesta, F. Estirado-de Cabo, E. García-Iglesias, F. González-Alegre, T. Fernández-Puntero, B. Montesano-Sánchez, L. Vicent-López, D. Cornejo-del Río, V. Fernández-García, P. J. Sánchez-Arroyo, V. Sabín-Rodríguez, C. López-López, S. Patrón-Barandio, P. Gómez-Campelo, P. PLoS One Research Article AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants with UT2DM, ranged between 45–74 years and lived in two districts in the north of metropolitan Madrid (Spain). The FINDRISC and MADRISC scores were evaluated using the area under the receiver operating characteristic curve method (ROC-AUC). Four different gold standards were used for UT2DM and any dysglycaemia, as follows: fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), HbA1c, and OGTT or HbA1c. Dysglycaemia and UT2DM were defined according to American Diabetes Association criteria. RESULTS: The study population comprised 1,426 participants (832 females and 594 males) with a mean age of 62 years (SD = 6.1). When HbA1c or OGTT criteria were used, the prevalence of UT2DM was 7.4% (10.4% in men and 5.2% in women; p<0.01) and the FINDRISC ROC-AUC for UT2DM was 0.72 (95% CI, 0.69–0.74). The optimal cut-off point was ≥13 (sensitivity = 63.8%, specificity = 65.1%). The ROC-AUC of MADRISC was 0.76 (95% CI, 0.72–0.81) with ≥13 as the optimal cut-off point (sensitivity = 84.8%, specificity = 54.6%). FINDRISC score ≥12 for detecting any dysglycaemia offered the best cut-off point when HbA1c alone or OGTT and HbA1c were the criteria used. CONCLUSIONS: FINDRISC proved to be a useful instrument in screening for dysglycaemia and UT2DM. In the screening of UT2DM, the simplified MADRISC performed as well as FINDRISC. Public Library of Science 2016-07-21 /pmc/articles/PMC4956208/ /pubmed/27441722 http://dx.doi.org/10.1371/journal.pone.0158489 Text en © 2016 Salinero-Fort et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Salinero-Fort, M. A. Burgos-Lunar, C. Lahoz, C. Mostaza, J. M. Abánades-Herranz, J. C. Laguna-Cuesta, F. Estirado-de Cabo, E. García-Iglesias, F. González-Alegre, T. Fernández-Puntero, B. Montesano-Sánchez, L. Vicent-López, D. Cornejo-del Río, V. Fernández-García, P. J. Sánchez-Arroyo, V. Sabín-Rodríguez, C. López-López, S. Patrón-Barandio, P. Gómez-Campelo, P. Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title | Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title_full | Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title_fullStr | Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title_full_unstemmed | Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title_short | Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study |
title_sort | performance of the finnish diabetes risk score and a simplified finnish diabetes risk score in a community-based, cross-sectional programme for screening of undiagnosed type 2 diabetes mellitus and dysglycaemia in madrid, spain: the spredia-2 study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956208/ https://www.ncbi.nlm.nih.gov/pubmed/27441722 http://dx.doi.org/10.1371/journal.pone.0158489 |
work_keys_str_mv | AT salinerofortma performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT burgoslunarc performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT lahozc performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT mostazajm performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT abanadesherranzjc performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT lagunacuestaf performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT estiradodecaboe performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT garciaiglesiasf performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT gonzalezalegret performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT fernandezpunterob performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT montesanosanchezl performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT vicentlopezd performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT cornejodelriov performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT fernandezgarciapj performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT sanchezarroyov performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT sabinrodriguezc performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT lopezlopezs performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT patronbarandiop performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT gomezcampelop performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study AT performanceofthefinnishdiabetesriskscoreandasimplifiedfinnishdiabetesriskscoreinacommunitybasedcrosssectionalprogrammeforscreeningofundiagnosedtype2diabetesmellitusanddysglycaemiainmadridspainthespredia2study |