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Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study

AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants w...

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Autores principales: Salinero-Fort, M. A., Burgos-Lunar, C., Lahoz, C., Mostaza, J. M., Abánades-Herranz, J. C., Laguna-Cuesta, F., Estirado-de Cabo, E., García-Iglesias, F., González-Alegre, T., Fernández-Puntero, B., Montesano-Sánchez, L., Vicent-López, D., Cornejo-del Río, V., Fernández-García, P. J., Sánchez-Arroyo, V., Sabín-Rodríguez, C., López-López, S., Patrón-Barandio, P., Gómez-Campelo, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956208/
https://www.ncbi.nlm.nih.gov/pubmed/27441722
http://dx.doi.org/10.1371/journal.pone.0158489
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author Salinero-Fort, M. A.
Burgos-Lunar, C.
Lahoz, C.
Mostaza, J. M.
Abánades-Herranz, J. C.
Laguna-Cuesta, F.
Estirado-de Cabo, E.
García-Iglesias, F.
González-Alegre, T.
Fernández-Puntero, B.
Montesano-Sánchez, L.
Vicent-López, D.
Cornejo-del Río, V.
Fernández-García, P. J.
Sánchez-Arroyo, V.
Sabín-Rodríguez, C.
López-López, S.
Patrón-Barandio, P.
Gómez-Campelo, P.
author_facet Salinero-Fort, M. A.
Burgos-Lunar, C.
Lahoz, C.
Mostaza, J. M.
Abánades-Herranz, J. C.
Laguna-Cuesta, F.
Estirado-de Cabo, E.
García-Iglesias, F.
González-Alegre, T.
Fernández-Puntero, B.
Montesano-Sánchez, L.
Vicent-López, D.
Cornejo-del Río, V.
Fernández-García, P. J.
Sánchez-Arroyo, V.
Sabín-Rodríguez, C.
López-López, S.
Patrón-Barandio, P.
Gómez-Campelo, P.
author_sort Salinero-Fort, M. A.
collection PubMed
description AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants with UT2DM, ranged between 45–74 years and lived in two districts in the north of metropolitan Madrid (Spain). The FINDRISC and MADRISC scores were evaluated using the area under the receiver operating characteristic curve method (ROC-AUC). Four different gold standards were used for UT2DM and any dysglycaemia, as follows: fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), HbA1c, and OGTT or HbA1c. Dysglycaemia and UT2DM were defined according to American Diabetes Association criteria. RESULTS: The study population comprised 1,426 participants (832 females and 594 males) with a mean age of 62 years (SD = 6.1). When HbA1c or OGTT criteria were used, the prevalence of UT2DM was 7.4% (10.4% in men and 5.2% in women; p<0.01) and the FINDRISC ROC-AUC for UT2DM was 0.72 (95% CI, 0.69–0.74). The optimal cut-off point was ≥13 (sensitivity = 63.8%, specificity = 65.1%). The ROC-AUC of MADRISC was 0.76 (95% CI, 0.72–0.81) with ≥13 as the optimal cut-off point (sensitivity = 84.8%, specificity = 54.6%). FINDRISC score ≥12 for detecting any dysglycaemia offered the best cut-off point when HbA1c alone or OGTT and HbA1c were the criteria used. CONCLUSIONS: FINDRISC proved to be a useful instrument in screening for dysglycaemia and UT2DM. In the screening of UT2DM, the simplified MADRISC performed as well as FINDRISC.
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spelling pubmed-49562082016-08-08 Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study Salinero-Fort, M. A. Burgos-Lunar, C. Lahoz, C. Mostaza, J. M. Abánades-Herranz, J. C. Laguna-Cuesta, F. Estirado-de Cabo, E. García-Iglesias, F. González-Alegre, T. Fernández-Puntero, B. Montesano-Sánchez, L. Vicent-López, D. Cornejo-del Río, V. Fernández-García, P. J. Sánchez-Arroyo, V. Sabín-Rodríguez, C. López-López, S. Patrón-Barandio, P. Gómez-Campelo, P. PLoS One Research Article AIM: To evaluate the performance of the Finnish Diabetes Risk Score (FINDRISC) and a simplified FINDRISC score (MADRISC) in screening for undiagnosed type 2 diabetes mellitus (UT2DM) and dysglycaemia. METHODS: A population-based, cross-sectional, descriptive study was carried out with participants with UT2DM, ranged between 45–74 years and lived in two districts in the north of metropolitan Madrid (Spain). The FINDRISC and MADRISC scores were evaluated using the area under the receiver operating characteristic curve method (ROC-AUC). Four different gold standards were used for UT2DM and any dysglycaemia, as follows: fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), HbA1c, and OGTT or HbA1c. Dysglycaemia and UT2DM were defined according to American Diabetes Association criteria. RESULTS: The study population comprised 1,426 participants (832 females and 594 males) with a mean age of 62 years (SD = 6.1). When HbA1c or OGTT criteria were used, the prevalence of UT2DM was 7.4% (10.4% in men and 5.2% in women; p<0.01) and the FINDRISC ROC-AUC for UT2DM was 0.72 (95% CI, 0.69–0.74). The optimal cut-off point was ≥13 (sensitivity = 63.8%, specificity = 65.1%). The ROC-AUC of MADRISC was 0.76 (95% CI, 0.72–0.81) with ≥13 as the optimal cut-off point (sensitivity = 84.8%, specificity = 54.6%). FINDRISC score ≥12 for detecting any dysglycaemia offered the best cut-off point when HbA1c alone or OGTT and HbA1c were the criteria used. CONCLUSIONS: FINDRISC proved to be a useful instrument in screening for dysglycaemia and UT2DM. In the screening of UT2DM, the simplified MADRISC performed as well as FINDRISC. Public Library of Science 2016-07-21 /pmc/articles/PMC4956208/ /pubmed/27441722 http://dx.doi.org/10.1371/journal.pone.0158489 Text en © 2016 Salinero-Fort et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Salinero-Fort, M. A.
Burgos-Lunar, C.
Lahoz, C.
Mostaza, J. M.
Abánades-Herranz, J. C.
Laguna-Cuesta, F.
Estirado-de Cabo, E.
García-Iglesias, F.
González-Alegre, T.
Fernández-Puntero, B.
Montesano-Sánchez, L.
Vicent-López, D.
Cornejo-del Río, V.
Fernández-García, P. J.
Sánchez-Arroyo, V.
Sabín-Rodríguez, C.
López-López, S.
Patrón-Barandio, P.
Gómez-Campelo, P.
Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title_full Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title_fullStr Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title_full_unstemmed Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title_short Performance of the Finnish Diabetes Risk Score and a Simplified Finnish Diabetes Risk Score in a Community-Based, Cross-Sectional Programme for Screening of Undiagnosed Type 2 Diabetes Mellitus and Dysglycaemia in Madrid, Spain: The SPREDIA-2 Study
title_sort performance of the finnish diabetes risk score and a simplified finnish diabetes risk score in a community-based, cross-sectional programme for screening of undiagnosed type 2 diabetes mellitus and dysglycaemia in madrid, spain: the spredia-2 study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956208/
https://www.ncbi.nlm.nih.gov/pubmed/27441722
http://dx.doi.org/10.1371/journal.pone.0158489
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