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Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations
Methyl-CpG binding protein 2 (MeCP2) is a widely abundant, multifunctional protein most highly expressed in post-mitotic neurons. Mutations causing Rett syndrome and related neurodevelopmental disorders have been identified along the entire MECP2 locus, but symptoms vary depending on mutation type a...
Autores principales: | Williams, Alison A., Mehler, Vera J., Mueller, Christina, Vonhoff, Fernando, White, Robin, Duch, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956225/ https://www.ncbi.nlm.nih.gov/pubmed/27442528 http://dx.doi.org/10.1371/journal.pone.0159632 |
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