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Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite’s Chloroquine Resistance Transporter

Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite’s digestive vacuole (DV). However, CQ resistance-conferring...

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Detalles Bibliográficos
Autores principales:	Richards, Sashika N., Nash, Megan N., Baker, Eileen S., Webster, Michael W., Lehane, Adele M., Shafik, Sarah H., Martin, Rowena E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956231/ https://www.ncbi.nlm.nih.gov/pubmed/27441371 http://dx.doi.org/10.1371/journal.ppat.1005725

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