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11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored

Dihydrotestosterone (DHT) is regarded as the most potent natural androgen and is implicated in the development and progression of castration resistant prostate cancer (CRPC). Under castrate conditions, DHT is produced from the metabolism of the adrenal androgen precursors, DHEA and androstenedione....

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Detalles Bibliográficos
Autores principales:	Pretorius, Elzette, Africander, Donita J., Vlok, Maré, Perkins, Meghan S., Quanson, Jonathan, Storbeck, Karl-Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956299/ https://www.ncbi.nlm.nih.gov/pubmed/27442248 http://dx.doi.org/10.1371/journal.pone.0159867

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