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Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint

The multi-functional molecular motor cytoplasmic dynein performs diverse essential roles during mitosis. The mechanistic importance of the dynein Light Intermediate Chain homologs, LIC1 and LIC2 is unappreciated, especially in the context of mitosis. LIC1 and LIC2 are believed to exist in distinct c...

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Detalles Bibliográficos
Autores principales:	Mahale, Sagar P., Sharma, Amit, Mylavarapu, Sivaram V. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956306/ https://www.ncbi.nlm.nih.gov/pubmed/27441562 http://dx.doi.org/10.1371/journal.pone.0159646

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