Cannabinoid 1 receptor knockout mice display cold allodynia, but enhanced recovery from spared-nerve injury-induced mechanical hypersensitivity

BACKGROUND: The function of the Cannabinoid 1 receptor (CB1R) in the development of neuropathic pain is not clear. Mounting evidence suggest that CB1R expression and activation may contribute to pain. Cannabinoid 1 receptor knockout mice (CB1R−/−) generated on a C57Bl/6 background exhibit hypoalgesi...

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Detalles Bibliográficos
Autores principales: Sideris, Alexandra, Piskoun, Boris, Russo, Lori, Norcini, Monica, Blanck, Thomas, Recio-Pinto, Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956369/
https://www.ncbi.nlm.nih.gov/pubmed/27206660
http://dx.doi.org/10.1177/1744806916649191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956369/
https://www.ncbi.nlm.nih.gov/pubmed/27206660
http://dx.doi.org/10.1177/1744806916649191

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